The filmmaker advised the actress - who stars in 'Hellboy II: The Golden Army' which is directed by Guillermo - to take hallucinogenic drug LSD to help "fix her head" because she is always negative about herself and never admits she is talented.
She told Arena magazine: "You know what Guillermo thinks? That I should go to Amsterdam and take an acid trip and it would fix my head. I think he could be right you know."
The actress hasn't yet acted on his advice, but won't rule out experimenting with the substance.
She added: "I've done some things to excess but I hate pot and I've never done acid or ecstasy. But if I was in the right frame of mind, in a pleasant, creative, chilled-out space, with just the right amount delivered by an Amsterdam technician that would be incredible."
©2008 AOL Australia Pty Limited in association with Bang Showbiz.All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
Related Article: Selma Blair 'shocked' Over Her Friends' Lesbian Crushes on Her
